I took Levaquin 500 mg x 2 days and almost immediately started having leg/calf cramps and swelling. My doctor d/c'd the drug, and 3 weeks later I still having relentless calf cramps. Thanks for your suggestions regarding change of antibiotics. I am now taking Cipro 500. After 2 days I have tendonitis in one leg. Not painful but walk with a limp. I took one does of Cipro, 500 mg in September of 2016 and within hours I was in agony, unable to put any weight on my right leg. I needed a cane for three days just to get around and it took a week for the pain to fully go away. I took amoxicillin last month and after two days of taking it with no problems, on the 3rd day, the exact same pain returned to my right leg. I was unable to walk for. Ciprofloxacin, also called Cipro. I had two doses of Cipro in the last six … Horrible Side Effects From Cipro for Prostatitis I would like to tell my experience with cipro after taking it for 8 days.I took cipro for 8 days for a chronic prostatitis prescribed for 24 days.Prescribed … Achilles Tendonitis from Cipro I took cipro for 7 days for a bladder infection and on the 5th day. Possibly, indefinitely. Tendonitis often results in scar-tissue forming in the tendon, which will remain in the tendon indefinitely until removed by some type of medical procedure, which can range from physical therapy to surgery. I first began suffering the pain and symptons of patellar tendonitis near the start of this year. It has taken a long time to recover from this painful condition and every now and then I still feel a 'tweak' of pain in my knee. This question has also been asked and answered here: How long does tendonitis last from taking Levaquin? I've was on Cipro and Prednisone at the same time and now I have tendonitis in my achilles tendon. I was taking 500mg of Cipro 2x a day and weaning off Prednisone at 10mg for about 5 days when this occurred. I stopped taking the Cipro yesterday and was wondering when this tendonitis will probably go away since I was taking it for. Cipro Tendonitis Is NOT Regular Tendonitis. Cipro Tendonitis is the little cousin of Levaquin Tendonitis. Both are in the 'Fluoroquinolone' family of antibiotics and create cytotoxic damage to connective tissue in the human body, as well as a variety of other side effects. Taking ciprofloxacin increases the risk that you will develop tendinitis (swelling of a fibrous tissue that connects a bone to a muscle) or have a tendon rupture (tearing of a fibrous tissue that connects a bone to a muscle) during your treatment or for up to several months afterward.